Important for strong bones, muscles and nerves, Calcium is the most abundant mineral in the human body: it represents 1 to 2 % of our bodyweight (1 to 1.5 kg) found at 99 % in the bones and the teeth. Besides its obvious function in the structure and the robustness of these tissues, Calcium is also involved in muscle contraction, neurons activity and blood coagulation., , As strong and solid as it is, the bone tissue is not a fixed but a dynamic structure: old bone tissue is constantly replaced by new one. This is achieved through active bone degradation, release of the Calcium in the blood circulation and reabsorption in newly-formed bone matrix., , Several factors can negatively influence circulating Calcium levels: unbalanced diets, age, lactation, menopause, use of glucocorticoids as well as of laxative. A small portion of Calcium is also naturally excreted in the urine. To compensate for decreasing blood Calcium levels, bone is degraded to release Calcium. This is why a constant supply of Calcium through the diet is primordial., , Not only the total amount of ingested Calcium is important to keep strong bones, muscles and nerves: from the food to the bones, Calcium follows a complex path. Without the help of two vitamins this would not even be possible. Fom the food to the blood: dietary Calcium is absorbed at the level of the intestine, by a specific transporter which is stimulated by Vitamin D3. This vitamin is further on responsible for the blood balance of Calcium and Phosphate meant for bone formation., , Fom the blood to the bone: circulating Calcium is brought to the bone matrix by proteins like osteocalcin. This is possible only if osteocalcin has been activated through a reaction dependent on Vitamin K. The right combination! The Calcium, Vitamin D3 and Vitamin K present in Doppelherz aktiv KalD3 tablets constitute the ideal combination to reach Calcium recommended daily intakes and ensure an optimal Calcium integration into the bones.